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In FBTC seizures, elevated lactic acid points to a surge in anaerobic glycolysis driven by the intense energy demands and hypoxia characteristic of prolonged neuronal activity

For instance, this study (146) utilized a neonatal maternal separation stress model in mice to simulate irritable bowel syndrome (IBS) and identified neuronal nitric oxide synthase (nNOS) as a novel and reliable biomarker for interstitial cells of Cajal stimulation in IBS